Titles: Quantitative Issues in Cell Biology & Statistical Design for Island Biology


Quantitative Issues in Cell Biology

We have two projects that lend themselves to statistical analysis. One involves labeling cell nuclei in a population of cells with a fluorescent probe, measuring the amount of fluorescence emitted using our FACS machine, and analyzing the data to determine how much DNA is present in each cell, and what is the complexity of the population.

A second method involves staining nuclei, measuring the amount of stain with a microscope coupled to a spectrometer, and determining the DNA content of a given cell's nucleus. These two projects could be coupled to give two different measures of a cell's DNA content.

Statistical Design for Island Biology

In my off-campus Island Biology series, students design research projects to explore the biology of marine, freshwater and terrestrial habitats on an island environment. Typically these projects have been descriptive rather than quantitative. The opportunity here would be to serve as a resource person for biology students to help design statistical analyses into their experiments, and/or develop a project on their own that involves good statistical design.

Faculty: Eric Cole, Biology

Helpful background: Biology 125 and 126, a basic statistics course.